Colchicine is a potent drug that influences body response to uric acid crystals which is responsible for the reduction of pain and swelling. Colcrys under the brand of Colchicine helps with the therapy and prevention of gout in adults, for adults’ cure of Familial Mediterranean Fever and children from 4 years old upward. Mitigate under the brand of Colchicine helps with the prevention of adults’ gout flares condition
Colchicine as a drug containing 0.6 mg in each capsule also contains the following ingredients:
- Lactose anhydrous;
- Colloidal silicon dioxide;
- Magnesium stearate;
- Microcrystalline cellulose;
- Sodium starch glycolate.
Colchicine capsule shell also contains:
- Titanium dioxide;
- Purified water;
- Brilliant Blue FCF;
- Quinoline Yellow.
Ensure you get your doctor notified on the drugs if it is at present in use or if you had stopped using before you use Colchicine with other medications. This may result in serious and unwanted side effects.
Mode of Indication, Dosage, and Duration of Treatment
The purchase of Colchicine is restricted only to the United States. You are not expected to get it online or from vendors. Ensure you take appropriate medical advice from a doctor in order to be on the safer side. The directions on the prescription label are meant to be followed. Ensure you take Colchicine in accordance with its required amount; not more or less or elongated than it is required. You can take Colchicine with or without a meal. Take Colchicine as early as possible because the late medication can make it less effective. Follow all instructions given by your doctor in relation to the dosage and duration of its use. Notify your doctor if there is no improvement after use or there is deterioration. If you decide to take Colchicine for a very long time, ensure you frequently go for medical tests.
Ensure you adhere to all the following precautionary measures before or when using Colchicine:
- Patients who are allergic to Colchicine should keep from it.
- Notify the doctor if you have experienced any of the following illnesses:
- Liver disease;
- Kidney disease.
- Notify the doctor if you are on medications like digoxin or cholesterol-lowering medications.
- Pregnant women and those who have the tendency to become pregnant should notify their doctors before the use of Colchicine.
- Lactating mothers should keep away from the use of Colchicine.
You are expected to call for immediate medical help when you begin to experience symptoms of allergic reactions such as:
- Swelling of the face, tongue, lips, or throat;
- Difficulty in breathing, and hive.
Typical side effects may include:
- Stomach pain;
In a situation whereby you forget to use your prescribed medicine, you can always take it at the moment of recollection. However, mind the time for the next dose if not close. Taking two doses at one time should be avoided.
Peradventure you take more than the prescribed doses, quickly see your doctor or call for emergency medical help.
The Colchicine drugs are contraindicated in patients with renal or hepatic impairment who are on medications that restrain both P-glycoprotein and CYP3A4 inhibitors. This may result in death or fatal Colchicine toxicity.
Interaction with other drugs
Ensure you notified the doctor before taking a new medication. If you are previously on some medications relating to the treatment with Colchicine, make sure you tell the doctor about them. There are some drugs that don’t interact with Colchicine. These are:
- Prescription and over-the-counter medicines;
- Herbal products.
The following drugs may result in dangerous effects if used while on Colchicine:
- Clarithromycin or telithromycin;
- HIV or AIDS drugs.
Avoid the intake of grapefruit, its juice and any of grapefruit products with Colchicine. The side effects may be dangerous.